mPEG-ACRL

Description

mPEG Acrylate (mPEG-ACRL) is a linear monofunctional PEG reagent with an acrylate group at one end of the PEG chain and a methoxy group at the other. This functional group enables various applications, including:  

• Polymerization: mPEG-ACRL shows reactivity towards radical and UV-initiated polymerization mechanisms, making it a candidate for PEG hydrogel synthesis.
• “Thiol-Ene Click Chemistry: The acrylate group reacts with thiols under mild conditions, enabling the formation of covalent bonds. This is useful for modifying surfaces, crosslinking polymers, and creating bioconjugates.  

Solubility:

• Widely soluble: mPEG acrylate is soluble in a wide range of organic solvents, including: Ethanol, Chloroform, DMF (Dimethylformamide), DMSO (Dimethyl sulfoxide), Acetone, THF (Tetrahydrofuran)

• Molecular Weight: Higher molecular weight mPEG acrylates tend to be less soluble in water but more soluble in organic solvents.
• Low Molecular Weights mPEG-acrylate are generally soluble in a variety of solvents, including: Water, Ethanol, Chloroform, Dimethylformamide (DMF)
• Temperature: Solubility generally increases with temperature.

Applications:

• Biomedical Research:
  • Drug delivery systems
  • Tissue engineering scaffolds
  • Protein and peptide modification
  • Biosensors
• Materials Science:
  • Polymer synthesis and modification
  • Coatings and surface modifications
  • Nanomaterials