mPEG-SIL

Description

mPEG silane, is a linear polyethylene glycol chain with a silane group at one end of a PEG chain and a methoxy group at the other end. PEG is a hydrophilic polymer known for its water solubility and biocompatibility, Silane PEG is a surface reactive product used to modify and deactivate glass, silica, metal, ceramics and hydroxylated surfaces and particles.

Structure and Properties:

• PEG silane consists of a PEG chain attached to a silane group, which is usually a trimethoxysilane or triethoxysilane.
• They exhibit excellent adhesion properties to various substrates.

Uses and Applications:

• Surface modification: PEG silanes are widely used to modify the surface properties of materials, making them more hydrophilic, biocompatible, or resistant to fouling.
• Coatings: They can be used to create coatings with enhanced water repellency, antifouling, and anti-corrosion properties.
• Biomaterials: PEG silanes are employed in the development of biomaterials for medical implants, tissue engineering, and drug delivery.
• Sensors: They are used in the fabrication of sensors for detecting various analytes, including biological molecules and chemicals.
• Chromatography: PEG silanes are used as stationary phases in chromatography to separate and analyze compounds.

Reaction Conditions:

• pH: The pH of the reaction medium can significantly influence the reactivity of PEG silanes. The optimal pH range for hydrolysis and condensation reactions is typically between 2 and 7.
• Temperature: The reaction temperature can affect the rate of hydrolysis and condensation. Higher temperatures generally accelerate the reaction.
• Solvent: PEGs are readily soluble in dichloromethane, chloroform, acetonitrile and water at room temperature.
• PEGs require heat to be soluble in toluene, methanol, ethanol, and isopropanol.
• PEGs are not soluble in ethers, ethylene glycol, hexane, and are not soluble in most alcohols at room temperature.

• Catalyst: Catalysts, such as acidic or basic catalysts, can be used to accelerate the hydrolysis and condensation reactions.