Biotin-PEG-SIL
$290.00 – $1,200.00
Biotin-PEG-Silane (Biotin-PEG-SIL) is available in molecular weights of 2,000, 3,400 and 5,000.
This product will be bottled in 500 mg, 1 gram or 5 gram bottles, depending on the item you order.
Other MW available as custom products contact our Sales Team.
Shipping charges will be calculated based on the total order
Description
Biotin-PEG-Silane is a linear heterobifunctional PEG reagent with a Biotin at one end of a PEG chain and a Silane at the other.
Key Features:
- Biotin: This vitamin B7 derivative binds strongly and specifically to avidin and streptavidin proteins. This property allows for the immobilization and detection of biotinylated molecules on surfaces. .
- PEG: PEG provides flexibility, water solubility, and reduces non-specific interactions, making it ideal for bioconjugation and surface modification.
- Silane: A reactive group that can form covalent bonds with hydroxyl groups on surfaces like glass, silica, or metal oxides. This enables the attachment of biotin-PEG molecules to various substrates
Applications:
- Surface Modification: Biotin-PEG-Silane can be used to modify surfaces with biotin, enabling the capture and immobilization of biotinylated proteins such as avidin or streptavidin-tagged biomolecules, nucleic acids, or other molecules
- Biosensors: By attaching biotin-PEG-silane to a sensor surface, it can be used to develop highly sensitive and specific biosensors for detecting various analytes. This is useful for biosensors, diagnostic assays, and drug delivery systems.
- Bioconjugation: The biotin moiety can be used to conjugate biotinylated molecules such as proteins, nanoparticles and biomolecules for various applications like drug delivery and imaging. This is valuable for creating bioconjugates with specific binding properties.
- Materials Science: Biotin-PEG-Silane can be used to create functional materials with specific binding properties, such as biocompatible coatings and affinity chromatography supports.
- Nanoparticle Functionalization: Biotin-PEG-Silane can be used to functionalize nanoparticles with biotin, allowing for targeted delivery and imaging applications.
Advantages:
- High Specificity: Biotin-avidin/streptavidin interactions are among the strongest non-covalent bonds in nature, ensuring high specificity in binding and detection.
- Water Solubility: PEG imparts water solubility, making the compound suitable for aqueous environments.
- Reduced Non-Specific Binding: PEG can reduce non-specific interactions, improving the selectivity of assays and reducing background noise.
Additional information
| Molecular Weight | 2000, 3400, 5000 |
|---|---|
| Bottle Size | 500 mg, 1 gram, 5 gram |
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